MTG-201 AND MTG-202 SELECTIVELY INDUCE APOPTOSIS IN CANCER CELLS THAT ARE REIC PROTEIN DEFICIENT DUE TO REDUCED EXPRESSION OF THE DICKKOPF-3 GENE. THIS DUAL MECHANICS OF ACTION BOTH DIRECTLY KILLS CANCER CELLS WHILE UPREGULATION THE IMMUNE SYSTEM AGAINST RESIDUAL DISEASE.
An unmet medical need in localized prostate cancer is for an effective treatment that preserves function. MTG Biotherapeutics seeks to provide men an option for treatment that is both safe and effective - and not have them wait until definitive therapy is needed or their cancer metastasizes.More
Mesothelioma is one of the most lethal cancers with a high unmet medical need. Current therapies have limited effect. There is an urgent need for a more effective treatment that gives hope of survival.
Invasive Bladder Cancer
Invasive Bladder Cancer is a poorly treated cancer where the cancer cells have spread beyond the inner lining of the bladder and into muscle tissue. If not treated, invasive bladder cancer can lead to the removal of the bladder or metastatic disease.
Hepatocellular Carcinoma (HCC) is a primary malignancy of the liver. While an Orphan disease in the United States, due to wide spread Hepatitis, HCC is a the third leading cause of cancer death worldwide.